Table 1.

tSNPS examined in iPLEX® assays

Assay 1		Assay 2
Gene	rs numbers	Gene	rs numbers
Endoglin (ENG)	rs10987746, rs10819309, rs10760505, rs11792480, rs10121110	TGFβR2	rs2043136, rs13075948, rs1346907, rs3773652, rs4955212, rs1155708, rs3773640, rs1036097, rs2082224, rs876688, rs744751, rs1078985, rs17025785, rs877572, rs5020833, rs6809777, rs6802220, rs9843942, rs6550005, rs3773644, rs3773645, rs13083813, rs12487185, rs13086588, rs6792117, rs3773663, rs4522809, rs11129420, rs995435, rs11924422
Transforming growth factor beta 1 (TGFβ1)	rs4803455, rs1800469, rs4803457, rs8179181, rs1800468, rs11466314
Transforming growth factor beta receptor 1 (TGFβR1)	rs6478974, rs420549, rs10739778
Activin receptor like kinase 1 (ALK1)	rs3759178, rs11169953, rs706819
Transforming growth factor beta receptor 2 (TGFβR2)	rs749794, rs3087465

Note. The online Human GenoTyping Tools and MassARRAY® Assay Designer v4.0 software (http://www.mysequenom.com) were used to design the iPLEX® assays. To optimize the multiplex reactions, tSNPs were grouped into Assay 1 or Assay 2.