Table 2. Characteristics of the Penn HDL INflammation and OXidation (PHINOX) cohort.
| Females (N=169) | Males (N=192) | |
|---|---|---|
|
| ||
| Median (interquartile range) | ||
| Age, years | 54 (48 to 61) | 49 (42 to 55) |
| Caucasian ethnicity (%) | 75 | 83 |
| Body mass index, kg/m2 | 26.6 (23.3 to 31.7) | 27.4 (25.5 to 30.2) |
| Waist circumference, cm | 89 (82 to 99) | 96 (90 to 104) |
| Blood pressure, mm Hg | ||
| Systolic | 123 (111 to 132) | 124 (116 to 133) |
| Diastolic | 75 (69 to 81) | 77 (72 to 84) |
| Fasting glucose, mg/dl | 73 (65 to 83) | 75 (66 to 84) |
| Total cholesterol, mg/dl | 202 (184 to 227) | 198 (169 to 218) |
| HDL cholesterol, mg/dl | 62 (49 to 74) | 48 (38 to 61) |
| Apolipoprotein A-I, mg/dl | 142 (125 to 160) | 124 (107 to 143) |
| Apolipoprotein A-II, mg/dl | 35 (32 to 39) | 33 (30 to 37) |
| LDL cholesterol, mg/dl | 120 (104 to 140) | 119 (101 to 142) |
| Apolipoprotein B, mg/dl | 83 (73 to 94) | 87 (75 to 98) |
| Triglycerides, mg/dl | 80 (60 to 122) | 91 (64 to 139) |
| C-reactive protein, mg/L | 1.6 (0.8 to 3.0) | 1.0 (0.6 to 2.1) |
| Serum amyloid A, μg/ml | 15.7 (8.6 to 26.2) | 9.3 (5.3 to 16.2) |
| Fibrinogen, mg/ml | 2.4 (2.0 to 2.9) | 2.2 (1.9 to 2.6) |
| Nitrated fibrinogen, nM | 43.1 (36.4 to 50.0) | 40.8 (34.8 to 49.0) |
| Coronary artery calcification | ||
| Mean score (±SD) | 83 ± 570 | 115 ±552 |
| Median score (IQR) | 0 (0 – 11.6) | 0 (0 to 42.3) |
| Common carotid artery intima-media thickness, (mm) | 0.68 (0.59 to 0.76) | 0.65 (0.57 to 0.75) |