Table 1.
Numbers of genes differentially regulated in mab-5 loss- and gain-of-function backgrounds
| mab-5 loss-of-function compared to wild type | Combined | |
|---|---|---|
| WT x e1239 lof DOWN |
10 (5 in WT x gk670 lof) |
381 DOWN in LOF combined |
| WT x gk670 lof DOWN |
33 |
(15 UP in GOF combined) |
| |
|
|
| WT x e1269 lof UP |
7 (4 in WT x gk670 lof) |
9 UP in LOF combined |
| WT x gk670 lof UP |
6 |
(1 DOWN in GOF combined) |
|
mab-5 gain-of-function compared to wild type and mab-5 loss-of-function |
Combined |
|
| WT x e1751 gof DOWN |
41 (10 in gk670 lof x e1751 gof) |
1291 DOWN in GOF combined |
|
e1239 lof x e1751 gof DOWN |
17 (10 in gk670 lof x e1751 gof) |
|
|
gk670 lof x e1751 gof DOWN |
92 (6 in each) |
|
| |
|
|
| WT x e1751 gof UP |
15 (5 in gk670 lof x e1751 gof) |
82 UP in GOF combined |
|
e1239 lof x e1751 gof UP |
24 (18 in gk670 lof x e1751 gof) |
|
| gk670 lof x e1751 gof UP | 65 (3 in each) | |
1These categories also included the retired gene R07B7.7, which was not included in further analysis.