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. 2013 Apr 22;110(19):7880–7885. doi: 10.1073/pnas.1300753110

Fig. 1.

Fig. 1.

Development of the C. elegans nervous system. (A) C. elegans reaches maturity roughly 63 h after fertilization. During this time, its body length increases from Inline graphic to Inline graphic (2224). (B) In the adult hermaphrodite worm, more than Inline graphic of the neurons are located in the head and about Inline graphic are found in the tip of the tail (based on data modified according to ref. 17, axis arbitrarily centered such that the origin is at the base of the head). Neurons are colored by ganglion membership (16): anterior [A], dorsal [B], lateral [C], ventral [D], retrovesicular [E], ventral cord [G], posterior lateral [F], preanal [H], dorsorectal [J], and lumbar [K]. (C) The total number of neurons (N, solid black), and connections (K, dashed blue), grows rapidly between 250 and 500 min after fertilization. Another burst of neurogenesis is observed at the end of the L1 larval stage (using data from ref. 17). (D) Plotting the number of synapses as a function of the number of neurons (yellow ●) reveals the presence of a phase transition. Before hatching, K grows as Inline graphic (solid blue line), whereas after hatching, K grows linearly with N (dashed green line). (Inset) Plot of the average nodal degree vs. N.