Fig. 4.

Thermoregulation and locomotor activity between Ift88 and ob/ob mice. (A) Body temperature of Ift88^flox/flox, Ift88^Δ/Δ, and ob/ob mice measured for baseline, after 30, 120, and 240 min of exposure to 4 °C, and at 270, 390, and 480 min during room temperature recovery. The ob/ob mice were pulled from the experiment due to an inability to thermoregulate. *P < 0.05, one-way ANOVA followed by post hoc Tukey's HSD test. (B) Locomotor activity at time point I comparing Ift88^flox/flox, Ift88^Δ/Δ, and ob/ob mice. *P < 0.05, **P < 0.01; one-way ANOVA followed by post hoc Tukey's HSD test. Numbers within parentheses or bars indicate number of animals.