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. 2013 Apr 8;5(4):270–275. doi: 10.18632/aging.100548

Table 1. Results and statistical analyses of life span assays.

Strain Treatment Max Life Span in Days ± SD Mean Life Span in Days ± SD n p-Value versus Control
N2 0.1 % DMSO control 28.1 ± 1.5 21.6 ± 1.2 11
clofibrate 0.1 μM 25.9 22.0 1 n. s. 0.8248
clofibrate 1 μM 27.2 22.6 1 n. s. 0.1877
clofibrate 10 μM 33.8 25.1 1 *** < 0.0001
clofibrate 10 μM 34.2 ± 0.9 23.0 ± 0.5 3 *** < 0.0001
bezafibrate 0.1 μM 32.0 23.3 1 * 0.0138
bezafibrate 1 μM 33.1 22.8 1 * 0.0137
bezafibrate 10 μM 34.4 22.9 1 ** 0.0078
bezafibrate 10 μM 32.5 ± 1.8 24.4 ± 0.7 3 *** 0.0002
fenofibrate 0.1 μM 34.6 22.5 1 * 0.0143
fenofibrate 1 μM 28.8 22.3 1 n. s. 0.1824
fenofibrate 10 μM 32.8 25.6 1 *** < 0.0001
fenofibrate 10 μM 30.2 ± 0.3 23.7 ± 1.1 3 * 0.0218
nhr-49
 ok2165 0.1 % DMSO control 17.2 ± 1.2 12.2 ± 0.4 3
bezafibrate 10 μM 17.7 ± 0.8 11.5 ± 0.2 3 n. s. 0.1606
clofibrate 10 μM 15.7 ± 0.4 11.0 ± 0.2 3 neg. s. < 0.0001
fenofibrate 10 μM 13.5 ± 0.2 9.5 ± 0.0 3 neg. s. < 0.0001
 gk405 0.1 % DMSO control 16.7 ± 3.6 11.0 ± 0.4 3
bezafibrate 10 μM 17.7 ± 3.7 11.4 ± 0.8 3 n. s. 0.0679
clofibrate 10 μM 17.5 ± 3.4 11.0 ± 0.3 3 n. s. 0.8962
fenofibrate 10 μM 14.5 ± 1.6 10.8 ± 0.2 3 n. s. 0.3035