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. Author manuscript; available in PMC: 2013 May 11.
Published in final edited form as: Science. 2012 Feb 9;335(6075):1503–1506. doi: 10.1126/science.1217697

Fig. 4.

Fig. 4

Rescue of cortical network activity with bexarotene. LFP recordings of Tg2576 or nontransgenic (NonTg) mice (12 to 14 months) gavaged with bexarotene (Bex) (100 mg kg−1 day−1) or vehicle (H2O) for 3 days after implantation of electrodes into PCX. PCX LFPs in response to the odor ethyl valerate in an awake nontransgenic, bexarotene-treated mouse. (A) Fifteen-to 35-Hz beta- and 35- to 75-Hz gamma-band power traces (second-order band pass). (B) PCX odor-evoked response magnitudes (2 s odor/2 s pre-odor) (n = 5 mice per group, four odor presentations per mouse; *P < 0.05, **P < 0.01, ***P < 0.001, mean ± SEM, two-tailed t tests of mean odor-evoked magnitudes within LFP bins). ns, not significant.