Table 3.
Independent Prognostic Factors for Overall Survival in Patients With Advanced HCC According to Multivariate Analysis
| Variable | Hazard Ratio for Death | 95% CI | P |
|---|---|---|---|
| No. of liver lesions, 1 v > 1 | 0.25 | 0.089 to 0.720 | .009 |
| Bilobar disease, yes v no | 1.76 | 1.08 to 2.784 | .0166 |
| Abdominal pain, yes v no | 2.29 | 1.551 to 3.39 | < .001 |
| Esophageal varices, yes v no | 1.61 | 1.069 to 2.437 | .0227 |
| ECOG PS, 2-3 v 0-1 | 2.95 | 1.868 to 4.666 | < .001 |
| Child Pugh stage, B v A | 1.88 | 1.243 to 2.832 | .0028 |
| Alkaline phosphatase | 1.96 | 1.007 to 3.817 | .04 |
| AFP | 1.24 | 1.106 to 1.393 | < .001 |
| AST | 3.47 | 1.799 to 6.686 | .002 |
Abbreviations: HCC, hepatocellular carcinoma; ECOG PS, Eastern Cooperative Oncology Group performance status; AFP, α-fetoprotein.