Figure 3. Diffusion weighted imaging (DWI) measurements with ROIs for patients.
Fractional anisotropy (FA; panel A), mean diffusivity (MD; panel B), axial diffusivity (AD; panel C), and radial diffusivity (RD; panel D) values for the 6 ROIs in sCJD, npRPD, and unimpaired control subjects. sCJD patients had significant reductions in MD (primarily due to changes in both AD and RD) in the caudate and pulvinar compared to npRPD and unimpaired controls. No significant changes in FA were seen for the ROIs among the three groups. *= p < 0.05.