Table 1.
Fibrocyte Marker Expression
Marker | Expression |
---|---|
Adhesion and Motility | |
CD9, CD11a, CD11b, CD11c, CD43, CD164, Mac2, LSP-1 |
+/++ |
CD34 | + |
CD29, CD44, CD81, ICAM-1, CD49 complex, CD81 |
+ |
Cell Surface Enzymes | |
CD10, CD172a | + |
CD13, Prolyl-4-hydroxylase | + |
FAP | + |
Scavenging receptors and host defense | |
CD14, CD68, CD163, CD206, CD209, CD35, CD36 |
+/− |
Fcγ receptors | |
CD16, CD32a, CD32b, CD32c | +/++ |
Chemokine receptors | |
CCR2, CCR5, CCR4, CCR7, CCR9, CXCR1, CXCR4, CXC3R1 |
+/++ |
Antigen Presentation | |
CD80, CD86, MHCI, MCHII | + |
Extracellular matrix | |
Collagen-I/III/IV, vimentin, tenascin | + |
Fibronectin, α-SMA | +/− |
Collagen V | ++ |
Glycosaminoglycans | |
Perlecan, Veriscan, Hyaluronan | ++/+ |
Decorin | + |
Miscellaneous | |
Semaphorin 7a | + |
CD115 | − |
Thy1.1 | + |
CD105 | + |
++ high level, + moderate, +/− conflicting reports or equivocal, - no expression