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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Neurobiol Aging. 2013 Mar 29;34(8):1977–1987. doi: 10.1016/j.neurobiolaging.2013.02.019

Figure 4. Morris water maze learning and memory task.

Figure 4

A day 1 was cue day. Days 4, 5, and 6 were training days, followed by a probe on day 7. Day 8 was reversal training, followed 72 h later by a reversal probe on day 11. B Based on the cumulative search index, a significant age-dependent decrease in the learning phase of the task (training days 1–6) was seen in control diet (CD) animals. C The cumulative index of the probe trial is shown. As shown in A and C, HFD had no impact on learning and memory performance. Means ± SEM are shown. * Significant aging differences @ p < 0.05.