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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Mol Cancer Ther. 2013 Feb 26;12(5):696–704. doi: 10.1158/1535-7163.MCT-12-0868

Figure 6. PF02341066 with radiation reduces Ki-67 proliferative marker and increases apoptosis in H3122 lung tumor xenograft model.

Figure 6

Histological sections were obtained from the tumors of the mice in each treatment group from the tumor volume study. Staining for Ki-67 was performed to assess cell proliferation and the number of positive cells was scored and graphed by averaging three repeated experiments (6A). Staining for active caspase-3 was performed to measure apoptosis and the number of positive cells was scored and graphed by averaging three repeated experiments (6B). Note: * denotes p < 0.05 compared to control.