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. Author manuscript; available in PMC: 2014 May 6.
Published in final edited form as: Mol Pharm. 2013 Apr 16;10(5):2031–2044. doi: 10.1021/mp400054e

Figure 5.

Figure 5

Biodistribution in the organs and targeting efficiency. (A) Exposure of the main organs as evaluated by area under the concentration versus time curve from 0 to 24h (AUClast) + standard error. (B) Relative targeting efficiency (RTE) of poly(ethylene glycol)-modified (SH-Gel PEG) and EGFR targeted thiolated gelatin nanoparticles (SH-Gel PEG Peptide) versus thiolated gelatin nanoparticles (SH-Gel NP). A value of 1 means similarity to SH-Gel NP targeting efficiency (TE). AUClast and TE were compared between nanoparticle types using an unpaired t-test: * p < 0.05, ** p < 0.01, and *** p < 0.001 for comparison to SH-Gel NP; + p < 0.05, ++ p < 0.01, +++ p < 0.001 for comparison to SH-Gel PEG.