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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Neurobiol Aging. 2013 Mar 23;34(8):2037–2051. doi: 10.1016/j.neurobiolaging.2013.02.001

Figure 5. SPT expression correlates with ceramide and Aβ levels.

Figure 5

Spearman's correlation tests demonstrate significant positive correlation between cortical SPTLC2 protein levels and (A) cortical d18:1; 16:0, (C) d18:1; 18:0, and (E) Aβ42 levels in the entire sample set (control chow, high-fat, diets and LCS administration) (n=38). Stronger positive correlations are observed between cortical SPTLC2 protein levels and (B) cortical d18:1; 16:0, (D) d18:1; 18:0, and (F) Aβ42 levels in control chow diet and LCS administered mice (n=35). The statistical significance of the correlation was determined by two-tailed T distribution tests.