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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Neurobiol Aging. 2013 Mar 23;34(8):2037–2051. doi: 10.1016/j.neurobiolaging.2013.02.001

Figure 6. Tau hyperphosphorylation is down-regulated with LCS administration.

Figure 6

(A) Quantification and (B) representation of western blot for tau hyperphosphorylation (probed with AT8) in control chow (n=12), high-fat (n=13) and LCS administered (n=13) mice. The expression levels were quantified by normalizing to β-actin and represented as a percentage of the control chow mice average expression. The statistical significances were determined by Mann-Whitney U tests. The brain sections were stained for Beilschowsky’s silver staining and captured with the camera on bright-field at 10× at the location denoted in red in Fig. 2C for (C–E) control chow, (F–H) high-fat and (I–K) LCS administration. The brain sections were stained with NF200 antibody and were captured with the camera on bright-field at 20× at the location denominated in red in Fig. 2C for (L–O) control chow, (P–S) high-fat and (T–W) LCS administration.