Table 2.

Immunologic and clinical characteristics of a sample of inpatients with newly-diagnosed HIV infection at two academic medical centers: 1994–2004.

	All	1994–1996	1997–2000	2001–2004	p-value
CD4 count (cells/μl)
Median	41	41	45	36	0.81
25th–75th percentile	19–138	12–100	19–158	20–92
Range	0–910	0–625	0–910	2–847
Initial CD4 count distribution#
≤50 cells/μl (%)	55	58	51	57	0.65
51–200 cells/μl (%)	30	34	29	28	0.73
>200 cells/μl (%)	15	8	20	15	0.16
Opportunistic infection
Any* (%)	76	80	73	77	0.53
Preventable§ (%)	53	60	51	48	0.33
Opportunistic infection or other AIDS-defining condition (%)	78	80	74	83	0.36

^#Initial CD4 count distribution excludes patients with missing CD4 count data. CD4 count data missing for 16 patients in Period 1; 1 patient in Period 2; and 1 patient in Period 3.

^*Opportunistic infections include candidiasis (oropharyngeal, vulvovaginal, or esophageal), cervical dysplasia, cervical intraepithelial neoplasia, cervical cancer, coccidioidomycosis, cryptococcosis, cryptosporidiosis, cytomegalovirus infection, herpes simplex virus infection, herpes zoster, histoplasmosis, isosporiasis, Mycobacterium avium complex, Mycobacterium tuberculosis, recurrent bacterial pneumonia, Pneumocystis jiroveci pneumonia, progressive multifocal encephalopathy, salmonella and toxoplasmosis.

^§Preventable opportunistic infections include Pneumocystis jiroveci pneumonia, toxoplasmosis, Mycobacterium tuberculosis, Mycobacterium avium complex, and cytomegalovirus infection.

^¶Other AIDS-defining conditions include HIV dementia, HIV encephalopathy, HIV wasting syndrome, Kaposi’s sarcoma, non-Hodgkins lymphoma, primary central nervous system lymphoma and progressive multifocal leukoencephalopathy.