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. Author manuscript; available in PMC: 2013 May 12.
Published in final edited form as: Cancer Treat Res. 2009;149:335–351. doi: 10.1007/978-0-387-98094-2_16

Figure 2.

Figure 2

Concepts of various 3D models to study OvCa cell adhesion/invasion. (A) OvCa cells cultured on a thin layer of ECM, (B) OvCa cells cultured on a thick layer of collagen , (C) OvCa cells cultured on a single layer of mesothelial cells or fibroblasts, (D) OvCa cells cultured on a single layer of mesothelial cells plated on ECM, (E) OvCa cells cultured on 3D organotypic model of human omentum. The 3D model is composed of fibroblasts embedded in a thick ECM layer and covered by primary human mesothelial cells.