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. Author manuscript; available in PMC: 2014 Mar 14.
Published in final edited form as: Cell. 2013 Mar 14;152(6):1298–1307. doi: 10.1016/j.cell.2013.02.012

Figure 4. LncRNAs regulate gene expression in the cytoplasm.

Figure 4

(A) The IncRNA TINCR interacts with STAU1 and target mRNAs containing the TINCR box motif, promoting their stability. (B) LncRNAs of the 1/2-sbsRNAs class hybridize with 3’ UTR containing Alu elements, and promotes the degradation of these target mRNAs. (C) Under stress conditions the IncRNA Antisense to Uchl1 moves from the nucleus to the cytoplasm and binds the 5’ end of the Uchl1 mRNA to promote its translation under stress conditions. (D) LincRNA-p21 interacts with and targets RcK to mRNAs resulting in translation inhibition.