Table 2.
Injection | 1 | 2 | 3 | 4 | 5 | 6 |
---|---|---|---|---|---|---|
Administered | S, C* | S, C | S, C | S, C | S, C | S, C |
Timeline | Day 1 | 2-3 days later |
2-3 days later |
2-3 days later |
2-3 days later |
2-weeks after Injection 5 |
Locomotor Track | Yes | No | No | No | Yes | Yes |
Measure | Novelty (S) and baseline cocaine - induced locomotor activity (C) |
Development of cocaine-induced locomotor sensitization |
Expression of cocaine-induced locomotor sensitization |
S, C saline then cocaine (10 mg/kg i.p.)