Table 2.
Anti-inflammatory effect of AF on paw edema induced by carrageenan.
| Time (H) | % Inhibition | ||||
|---|---|---|---|---|---|
| Indomethacin | Senecio salignus | ||||
| 8 mg/kg | 50 mg/kg | 100 mg/kg | 200 mg/kg | 400 mg/kg | |
| 1 | 15.1 ± 2.8* | 10.3 ± 4.02* | 15.03 ± 3.1* | 17.5 ± 2.3* | 27.5 ± 3.8 |
| 2 | 28.3 ± 3.8* | 21.3 ± 2.4* | 27.8 ± 3.1* | 29.1 ± 3.1* | 34.5 ± 2.2* |
| 3 | 43.4 ± 3.2* | 26.6 ± 2.1 | 47.5 ± 4.02* | 44.6 ± 3.8* | 57.3 ± 2.6 |
| 4 | 61.1 ± 3.8* | 37.2 ± 4.6 | 58.9 ± 2.8* | 63.5 ± 2.2* | 70.3 ± 4.5 |
| 5 | 62.2 ± 3.9* | 38.9 ± 3.3 | 60.1 ± 4.7* | 62.9 ± 2.04* | 80.1 ± 4.5 |
Results are expressed as percentage of inhibition and mean of eight determinations ± SE. One-way ANOVA, Dunnett test *P < 0.05 for comparison of S. salignus with indomethacin-treated groups.