Table 3.
Mean (±S.D.) morphometric values for colon toxicity indicators in control mice (0.000 mg/g extract, N=4) and mice administered 0.125 mg/g (N=8), 0.5 mg/g (N=7), and 1.0 mg/g (N=6) of muricid extract (ME).
| Colon region | ME dose (mg/g) |
Crypt height (cells/crypt) |
Crypt cell density (cells/µm) |
|---|---|---|---|
| Proximal | 0.000 | 13.66 ± 1.90 | 0.18 ± 0.05 |
| 0.125 | 13.78 ± 2.31 | 0.17 ± 0.05 | |
| 0.500 | 14.00 ± 2.64 | 0.19 ± 0.06 | |
| 1.000 | 13.50 ± 2.71 | 0.18 ± 0.05 | |
|
| |||
| Distal | 0.000 | 22.77 ± 3.34 | 0.21 ± 0.07 |
| 0.125 | 23.23 ± 3.53 | 0.19 ± 0.05 | |
| 0.500 | 22.43 ± 3.81 | 0.18 ± 0.04 | |
| 1.000 | 23.05 ± 4.01 | 0.19 ± 0.04 | |