Effect of alcohol consumption on IGF-I in plasma (A) and muscle IGF-I (B), muscle IGF binding protein (IGFBP)-4 (C), and IGFBP-5 (D) mRNA content in gastrocnemius of adult and aged female rats. mRNA values were normalized to L32. Values are expressed as means ± SE; n = 8 or 9 rats per group. a,b,cValues with different letters are statistically different (P < 0.05), while values with the same letter are not statistically different.