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. 2013 Apr 16;2013:945245. doi: 10.1155/2013/945245

Table 5.

BIOCART terms distribution of upregulated genes (downexpression level of miRNAs) of TCM syndromes in CHB.

Category Term Genes
LGDHS/normal Prion pathway RPSA, BCL2, LAMC1, DNAJB1, HSPA5, LAMB1, PRNP
LDSDS/normal Signaling pathway from G-protein families RPS6KA3, GNAQ, MAP2K1, GNB1, JUN, PPP3CA
LKYDS/normal ALK in cardiac myocytes TGFBR1, SMAD5, TGFBR2, SMAD4, BMPR2, BMP7, ATF2, BMPR1A, ACVR1, APC
Melanocyte development and pigmentation pathway CREB1, BCL2, MITF, KITLG, KIT
LGDHS/LDSDS No No
LDSDS/LKYDS Cell cycle: G1/S check point E2F1, SMAD4, SMAD3, CDK6, RB1, CDK4, ATM, CDC25A, CCND1, CDKN1A, CDKN1B, DHFR, CDKN2A, HDAC1, CDKN2B, CCNA1
p53 signaling pathway E2F1, CDKN1A, CCND1, BCL2, BAX, PCNA, APAF1, RB1, CDK4, TIMP3, ATM