Table 2.
Clinical and biological characteristics of 100 patients with chronic hepatitis B and 25 normal subjects.
| Group A | Group B | Group C | |
|---|---|---|---|
| (n = 50) | (n = 50) | (n = 25) | |
| Age (years) | 36 (22, 58) | 37.5 (17, 50) | 35 (20, 57) |
| Gender (M/F) | 50 (43/7)* | 50 (44/6)* | 25 (15/10) |
| Course of disease (years) | 4 (0.6, 23) | 7.5 (0.6, 27) | — |
| TBIL (μmol/L) | 14.21 (5.2, 81.21) | 18.19 (8.65, 245.41) | 14.9 (6.9, 20.5) |
| DBIL (μmol/L) | 5.75 (2.5, 62.9)* | 6.35 (2.5, 201.4)* | 4.2 (3, 5.3) |
| IDBIL (μmol/L) | 10.15 (1.3, 28.7) | 11.75 (4.5, 44) | 10.7 (3.9, 15.9) |
| ALT (IU/L) | 66 (23, 365)* | 67.5 (22, 584)* | 17 (10, 31) |
| AST (IU/L) | 39.5 (25, 131)* | 37.5 (20, 286)* | 19 (14, 35) |
| GGT (IU/L) | 39.5 (7, 436)* | 45 (5, 634)* | 19 (10, 63) |
| ALP (IU/L) | 84 (47, 211)* | 96 (39, 182)* | 53 (13, 96) |
| TP (g/L) | 73.5 (53, 86) | 74 (61, 84) | 72 (62, 79) |
| ALB (g/L) | 30 (9, 48)* | 28 (19, 49)* | 44 (38, 63) |
| TBA (μmol/L) | 16 (2, 311)* | 17.5 (2, 390)* | 8 (5, 12) |
| HBsAg (IU/mL) | 250 (15.25, 250)* | 250 (0.27, 250)* | 0.01 (0, 0.02) |
| HBeAg (S/CO) | 37 (13) | 30 (20) | — |
| log DNA (copies/mL) | 5.03 (3.05, 9.24) | 5.01 (3.13, 8.04) | — |
Statistical analysis of data among groups was performed by the Kruskal-Wallis test, and significant differences were compared with Group C (*P < 0.05).