Table 4.
Kinetics of inflammatory molecules in patients with bacterial infection during antibiotic therapy.
| Analyte (pg/mL) | Day 1 | Day 3 | Day 7 | Control | P value |
|---|---|---|---|---|---|
| IL-1Ra | 11,618* | 3,247 | 2,604 | 1,544 | <0.001 |
| (42,790) | (11,492) | (8,607) | (8,768) | ||
| IL-2 | 22.5* | 21.4* | 19.5* | 11.9 | <0.013 |
| (36.5) | (57.4) | (71.2) | (26.1) | ||
| IL-6 | 39.1* | 1.9 | 0.4 | 0.4 | <0.001 |
| (1,597) | (150) | (95.8) | (0.0) | ||
| IL-8 | 26.6* | 21.2 | 14.6 | 6.9 | <0.039 |
| (350) | (648) | (58) | (54) | ||
| TNF-α | 10.8* | 5.5 | 4.5 | 0.6 | <0.020 |
| (61.0) | (31.2) | (16.8) | (25.8) | ||
| MCP-1 | 326 | 187 | 231 | 205 | n.s. |
| (7,524) | (210) | (287) | (279) | ||
| MIP-1β | 91.0* | 76.8 | 60.4 | 54.6 | <0.025 |
| (1,699) | (275) | (161) | (91.2) |
Data are presented as median (range); n.s.: not significant; *P < 0.05, time point versus control.