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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Neurobiol Aging. 2013 Jun;34(6):1610–1620. doi: 10.1016/j.neurobiolaging.2012.12.014

Figure 1.

Figure 1

Heat map of selected genes displaying expression levels from microarray analysis in 6-month-old mice that received cytokine cocktails. [A] Represents top 500 gene transcripts differentially regulated by CKT-1 (TNF-α, IL-1β, IL-12) or CKT-2 (IL-4, IL-13) compared to vehicle (PBS). Overall, more transcripts were changed by the CKT-1 cocktail. [B, C, D] Represent heat expression maps for the top 20 gene transcripts significantly up (red) or down (green) regulated from Ingenuity pathway analysis. [B.1, C.1, D.1] displaying gene symbols and expression values (Log2 scale). Panels [B, B.1] represent CKT-1 compared to vehicle, [C, C.1] represents CKT-2 compared to vehicle, [D, D.1] represent CKT-2 compared to CKT-1.