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. Author manuscript; available in PMC: 2013 May 13.
Published in final edited form as: Eur J Clin Nutr. 2012 Aug 1;66(10):1082–1092. doi: 10.1038/ejcn.2012.85

Table 5.

Characteristics of studies identified by systematic review and included in the meta-analysis

Author Country/
countries
Age (yrs)/ sex/
years of
follow-up
Exposure
assessment
Highest intake
category/ reference
category *
Number of diabetes cases/
assessment of type 2 diabetes/
assessment criteria (if stated)
Exclusion criteria Variables adjusted for in
analyses
Current results
from EPIC-
InterAct study
France, Germany,
The Netherlands,
UK, Italy,
Sweden, Denmark,
and Spain
40-79/ men &
women/ 11
Country specific
dietary
questionnaires
FV: 8.71/2.13
Fruit: 5.39/0.75
Veg: 3.94/0.88
GLV: 5.93/0.05
RV: 3.87/0.12
10 821/ Self-report (self-report of
doctor diagnosed diabetes, anti-
diabetic drug use), linkage to
primary and secondary care
registers, medication use (drug
registers), hospital admissions and
mortality data with a coding for
diabetes, local and national diabetes
and pharmaceutical registers
Incomplete dietary information;
extreme values for total energy intake
(top or bottom 1% of the original EPIC
study sample); missing information on
potential confounding variables;
diabetes, myocardial infarction or
stroke at baseline.
Age, sex, centre, country,
education level, BMI, physical
activity level, smoking status,
total energy intake, alcohol
intake
Villegas et al,
2008 30
China (Shanghai
Women’s Health
Study)
40-70/ women/
4.6
77 item food
frequency
questionnaire. Mean
of intake between
baseline and follow-
up used.
Fruit: 5.57/1.09
Veg: 5.35/1.52
GLV: 11.91/2.45
RV: 1.51/0.04
1 608/ Self-report (self-report of
doctor diagnosed diabetes, glucose
test history and/or use of
hypoglycaemic medication)/ ADA
1997 criteria
<40 yrs or > 70 yrs; type 2 diabetes,
cancer, or cardiovascular disease
present at baseline; extreme values for
total energy intake (<2,090 or >14,630
KJ/d).
Age, EI, meat intake, BMI,
WHR, smoking, alcohol, PA,
income level, education level,
occupational status,
hypertension
Bazzano et al,
2008 7
USA (Nurses’
Health Study)
30-55/ women/
18
61 item food
frequency
questionnaire
F&V: 7.66/2.35
Fruit: 2.64/0.46
Veg: 5.40/1.61
GLV: 10.36/1.75
4 529/ Self-report with questionnaire
(asking about symptoms, diagnostic
tests, and treatments) / NDDG
criteria before 1997, ADA criteria
after 1997
Extreme values for total energy intake
(<600 or >3,500 Kcal/d); ≥12 FFQ
items left blank; diabetes or missing
data for diabetes, cancer, or
cardiovascular disease present at
baseline; missing date for diabetes at
follow-up
Age, BMI, PA, family history
of diabetes, postmenopausal
hormone use, alcohol use,
smoking, EI
Montonen et al,
2005 29
Finland (Finnish
Mobile Clinic
Health
Examination
Survey)
40-69/ men &
women/
23
Diet history
interview
Fruit: 2.17/0.0
Veg: 1.94/0.30
GLV: 4.55/0.39
383/ Social Insurance Institution
nationwide register of persons
receiving drug reimbursement (for
diabetes)
<40 yrs or > 69 yrs; extreme values for
total energy intake (<800 or >6,000
Kcal/d); pregnant women; diabetes at
baseline.
Age, sex, BMI, EI, smoking,
family history of diabetes,
geographic area
Liu et al, 2004 10 USA (Women’s
Health Study)
≥45/ women/
8.8
131 item food
frequency
questionnaire
F&V: 10.16/2.54
Fruit: 3.91/0.62
Veg: 6.84/1.47
GLV: 9.94/0.98
RV: 7.00/0.49
1 614/ Self-report of doctor
diagnosed diabetes (with
confirmation from different sources
including: bloods, telephone
interview, supplementary
questionnaire, contact with doctor)
Diabetes present at baseline Age, smoking, EI, alcohol use,
BMI, PA, history of
hypertension, history of high
cholesterol, family history of
diabetes
Ford and Mokdad,
2001 8
USA (NHANES I) 25-74/ men &
women/ 20
24-hour recall F&V: ≥6.5/0.0 1 018/ Self-report of doctor
diagnosed diabetes, hospitalisation
record ICD-9-CM: 250, death
certificate ICD-9: 250
Not white or African American;
insufficient information of diabetes
status; prevalent diabetes; pregnant
women; and those with missing data
for covariates
Age, sex, smoking status,
systolic BP, cholesterol
concentration, antihypertensive
medication, recreational
exercise, non-recreational
activity, alcohol use, BMI,
education
Meyer et al, 2000
11
USA (Iowa
Women’s Health
Study)
55-69/ women/
6
127 item food
frequency
questionnaire
F&V: 8.86/2.57
Fruit: 3.36/0.57
Veg: 5.93/1.57
1 141/ Self-report (self-report of
doctor diagnosed diabetes, anti-
diabetic drug use)
Extreme values for total energy intake
(<2,510 or >20,920 KJ/d); ≥30 FFQ
items left blank; diabetes at baseline
Age, EI, BMI, WHR, education,
smoking, alcohol intake, PA
*

Veg=vegetables; GLV=green leafy vegetables; RV=root vegetables; F&V, fruit and vegetables are in portions/d; GLV and RV are in portions/week.

BMI=body mass index; EI=energy intake; WHR=waist-to-hip ratio; PA=physical activity; BP=blood pressure.

Note: Harding et al. paper not included in systematic review as those data are included within EPIC-InterAct.