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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Stem Cells. 2013 May;31(5):1001–1009. doi: 10.1002/stem.1343

Fig. 4.

Fig. 4

Partial recovery of germ cell pool size in adult Lin28a KO males. (A) A representative photographs of 5-month-old Lin28a +/− and −/− mice and their testes. Bar 5mm. (B–F) Testis weight (B), testis weight relative to body weight (C) in 5- to 6-month-old Lin28a +/− and −/− mice. N=6. (D–F) Total epididymal sperm count per mouse (D), percentage of motile sperms (E), and percentage of abnormal sperms (F) in 7- to 8-month-old Lin28a +/− and −/− mice. N=3–4. (G) H&E and immunostaining of 6-month-old Lin28a +/− and −/− testes. (H–I) Number of Mvh+ germ cells per tubule (H) and number of tubules containing Ki67+ cells (I) in 6- to 8-month-old Lin28a +/− and −/− adult testes. N=5. ** p<0.01. Error bars represent SEM. Scale bars 100 µm.