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. Author manuscript; available in PMC: 2013 May 13.
Published in final edited form as: Nature. 2012 Jan 18;481(7381):295–305. doi: 10.1038/nature10761

Figure 1. Morphology of pluripotent stem cell types.

Figure 1

Mouse ES (a) and iPS (b) cells form dome-shaped, refractile colonies. These colonies are in contrast to the flat morphology of mouse epiblast-derived stem cells (f), which resemble human ES (d) and iPS (e) cells. Human iPS cells induced into a naive pluripotent state by treatment with chemical inhibitors82–85 (c) parallel the morphology of mouse ES and iPS cells. Scale bars, 50 μm.