Table 1.
Study population mean demographics by case status. Range is provided in parentheses
| Characteristic | LOAD cases
|
Cognitively normal controls
|
||
|---|---|---|---|---|
| Discovery set (n = 12) | Full set (n = 25) | Discovery set (n = 12) | Full set (n = 25) | |
| Neuropathological diagnosis | High likelihood | High lkelihood | Control n = 11 | Control n = 24 |
| AD n = 11 | AD n = 21 | Other n = 1 | Other n = 1 | |
| Intermediate | Intermediate | |||
| Likelihood n = 1 | Likelihood n = 4 | |||
| Braak stage | 4.7 (2–6) | 4.8 (2–6) | 1.3 (1–2) | 1.5 (1–2) |
| Age | 79.6 (69–94) | 78.2 (61–94) | 79.9 (69–95) | 78.3 (61–95) |
| Gender | ||||
| Female | 6 | 9 | 6 | 9 |
| Male | 6 | 16 | 6 | 16 |
| Post mortem interval (h) | 9.6 (3–24) | 9.5 (3–27.5) | 16.3 (6–24.5) | 16.0 (5–28) |
| Years in storage | 10.75 (5–17) | 10.5 (3–18) | 13.2 (3–20) | 13.2 (2–21) |
| Race | Caucasian (n = 12) | Caucasian (n = 25) | Caucasian (n = 12) | Caucasian (n = 25) |
| Age of onset | 69.1 (59–78) | NA | NA | |
| MMSE | 11.7 (0–28) missing = 1 | 12.9 (0–30) missing = 2 | 26.8 (25–28) missing = 10 | 26 (24–28) missing = 16 |
| # Years from diagnosis to death | 5.1 (1–12) | 5.2 (1–12) | NA | NA |
| APOE Genotype | ||||
| 2/2 | 2 | 2 | 3 | 6 |
| 2/3 | 1 | 1 | 0 | 1 |
| 2/4 | 0 | 1 | 0 | 0 |
| 3/3 | 3 | 7 | 6 | 13 |
| 3/4 | 5 | 13 | 1 | 3 |
| 4/4 | 1 | 1 | 1 | 1 |
| Missing | 0 | 0 | 1 | 1 |