Table 1.
Group | Histological parameter | Tetracycline | Chlorhexidine gluconate | Myrrh | Control |
---|---|---|---|---|---|
24 hours | Mucosal continuity | 0 | 0 | 0 | 0 |
Granulation tissue | 0 | 0 | 0 | 0 | |
Necrosis | 0 | 0 | + | ++ | |
Vascularity | + | ++ | + | + | |
PMNs | +++ | + | ++ | +++ | |
Macrophages | 0 | 0 | 0 | 0 | |
Lymphocytes | 0 | 0 | 0 | 0 | |
Plasma cells | ++ | + | ++ | ++ | |
Fibroblasts | 0 | 0 | 0 | 0 | |
48 hours | Mucosal continuity | 0 | 0 | 0 | 0 |
Granulation tissue | 0 | 0 | 0 | 0 | |
Necrosis | 0 | + | + | ++ | |
Vascularity | ++ | ++ | ++ | ++ | |
PMNs | ++ | + | + | +++ | |
Macrophages | + | + | + | + | |
Lymphocytes | + | + | + | + | |
Plasma cells | ++ | + | + | ++ | |
Fibroblasts | 0 | 0 | + | 0 | |
1 week | Mucosal continuity | +++ | +++ | +++ | +++ |
Granulation tissue | +++ | ++ | ++ | ++ | |
Necrosis | 0 | 0 | 0 | 0 | |
Vascularity | ++ | + | +++ | + | |
PMNs | 0 | 0 | + | 0 | |
Macrophages | + | + | + | +++ | |
Lymphocytes | + | + | 0 | + | |
Plasma cells | ++ | ++ | ++ | ++ | |
Fibroblasts | ++ | ++ | ++ | ++ | |
2 weeks | Mucosal continuity | +++ | +++ | +++ | +++ |
Granulation tissue | ++ | ++ | ++ | ++ | |
Necrosis | 0 | 0 | +++ | 0 | |
Vascularity | + | + | + | + | |
PMNs | 0 | 0 | +++ | 0 | |
Macrophages | + | + | + | + | |
Lymphocytes | 0 | 0 | + | 0 | |
Plasma cells | + | + | ++ | + | |
Fibroblasts | ++ | ++ | + | ++ | |
4 weeks | Mucosal continuity | +++ | +++ | +++ | +++ |
Granulation tissue | + | + | ++ | + | |
Necrosis | 0 | 0 | 0 | 0 | |
Vascularity | + | + | + | + | |
PMNs | 0 | 0 | 0 | 0 | |
Macrophages | 0 | 0 | + | 0 | |
Lymphocytes | 0 | 0 | 0 | 0 | |
Plasma cells | + | + | ++ | + | |
Fibroblasts | + | + | ++ | + |
Note: 0 = none, + = mild, ++ = moderate, +++ = severe/dense.
Abbreviation: PMNs, polymorphonuclear leukocytes.