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. 2011 Aug 30;3:53–58. doi: 10.2147/CCIDEN.S24064

Table 1.

Histological parameter scores for all groups

Group Histological parameter Tetracycline Chlorhexidine gluconate Myrrh Control
24 hours Mucosal continuity 0 0 0 0
Granulation tissue 0 0 0 0
Necrosis 0 0 + ++
Vascularity + ++ + +
PMNs +++ + ++ +++
Macrophages 0 0 0 0
Lymphocytes 0 0 0 0
Plasma cells ++ + ++ ++
Fibroblasts 0 0 0 0
48 hours Mucosal continuity 0 0 0 0
Granulation tissue 0 0 0 0
Necrosis 0 + + ++
Vascularity ++ ++ ++ ++
PMNs ++ + + +++
Macrophages + + + +
Lymphocytes + + + +
Plasma cells ++ + + ++
Fibroblasts 0 0 + 0
1 week Mucosal continuity +++ +++ +++ +++
Granulation tissue +++ ++ ++ ++
Necrosis 0 0 0 0
Vascularity ++ + +++ +
PMNs 0 0 + 0
Macrophages + + + +++
Lymphocytes + + 0 +
Plasma cells ++ ++ ++ ++
Fibroblasts ++ ++ ++ ++
2 weeks Mucosal continuity +++ +++ +++ +++
Granulation tissue ++ ++ ++ ++
Necrosis 0 0 +++ 0
Vascularity + + + +
PMNs 0 0 +++ 0
Macrophages + + + +
Lymphocytes 0 0 + 0
Plasma cells + + ++ +
Fibroblasts ++ ++ + ++
4 weeks Mucosal continuity +++ +++ +++ +++
Granulation tissue + + ++ +
Necrosis 0 0 0 0
Vascularity + + + +
PMNs 0 0 0 0
Macrophages 0 0 + 0
Lymphocytes 0 0 0 0
Plasma cells + + ++ +
Fibroblasts + + ++ +

Note: 0 = none, + = mild, ++ = moderate, +++ = severe/dense.

Abbreviation: PMNs, polymorphonuclear leukocytes.