Schematic representation of the lentiviral vectors used during this study. The components shown are the long terminal repeat (LTR), the self-inactivating long terminal repeat (Sin-LTR), the HIV rev-response and central polypurine tract elements (RRE, cPPT), the splice donor (SD), the splice acceptor (SA), the woodchuck hepatitis virus posttranscriptional regulatory element (WPRE), the liver-specific TTR promoter (TTR), the internal ribosome entry site (IRES), the enhanced green fluorescent protein (eGFP), and the mouse Hamp and Hfe cDNA sequences.