Table 2.
Maternal and non-maternal behaviors of postpartum rats after BSTv infusion of idazoxan. Groups with different superscript letters are statistically different from one another (post-hoc p ≤.017).
Idazoxan Dose | |||||
---|---|---|---|---|---|
0 μg (n = 9) | 10 μg (n = 7) | 20 μg (n = 9) | F (2,22) | p | |
Latency (s) | |||||
Contact pups | 5 ± 2 | 5 ± 3 | 3 ± 1 | 0.26 | 0.771 |
Retrieve first pup* | 9 ± 3 | 119 ± 82 | 170 ± 83 | 1.54 | 0.237 |
Hover over pups after all in nest | 73 ± 61 | 344 ± 267 | 521 ± 299 | 1.08 | 0.358 |
Nurse pups after all in nest | 419 ± 112a | 863 ± 241ab | 1156 ± 245b | 3.55 | 0.046 |
Duration (s) | |||||
Lick pups | 192 ± 70 | 177 ± 72 | 130 ± 49 | 0.27 | 0.764 |
Nest/burrow | 81 ± 49 | 28 ± 14 | 89 ± 74 | 0.33 | 0.734 |
Self-grooming | 111 ± 37a | 196 ± 42a | 432 ± 103b | 5.79 | 0.096 |
Explore cage | 137 ± 48 | 326 ± 94 | 467 ± 151 | 2.50 | 0.106 |
Hover over pups | 546 ± 114 | 508 ± 195 | 554 ± 149 | 0.03 | 0.976 |
Nursing | 1767 ± 167a | 1166 ± 311ab | 787 ± 214b | 5.15 | 0.015 |
Total time spent with pups | 2313 ± 122a | 1673 ± 311ab | 1340 ± 306b | 4.05 | 0.032 |
% Time nursing after pups in nest | 68 ± 6a | 47 ± 12ab | 33 ± 10b | 4.12 | 0.030 |
Litter Weight Gain (g) | 2.33 ± 0.37a | 1.37 ± 0.58ab | 0.82 ± 0.24b | 4.08 | 0.031 |
non-responders assigned latency of 600 sec.