Table 3.
Maternal and non-maternal behaviors of postpartum rats after mPOA infusion of idazoxan.
| Idazoxan Dose | ||||
|---|---|---|---|---|
| 0 μg (n = 8) | 20 μg (n = 7) | t13 | p | |
| Latency (s) | ||||
| Contact pups | 1 ± 1 | 11 ± 4 | 2.35 | 0.035 |
| Retrieve first pup* | 3 ± 1 | 313 ± 104 | 3.19 | 0.007 |
| Hover over pups after all in nest | 77 ± 42 | 858 ± 386 | 2.16 | 0.050 |
| Nurse pups after all in nest | 529 ± 57 | 1458 ± 239 | 4.03 | 0.001 |
| Duration (s) | ||||
| Lick pups | 68 ± 26 | 48 ± 29 | 0.51 | 0.619 |
| Nest/burrow | 1 ± 1 | 5 ± 3 | 1.36 | 0.196 |
| Self-grooming | 85 ± 14 | 442 ± 73 | 5.15 | 0.0002 |
| Explore cage | 88 ± 21 | 621 ± 136 | 4.16 | 0.001 |
| Hover over pups | 349 ± 42 | 155 ± 53 | 2.89 | 0.013 |
| Nurse pups | 1996 ± 86 | 615 ± 228 | 5.98 | 0.0001 |
| Total time spent with pups | 2345 ± 88 | 770 ± 246 | 6.35 | 0.0001 |
| % Time nursing after pups in nest | 74 ± 3 | 29 ± 11 | 4.35 | 0.0008 |
| Litter Weight Gain (g) | 3.01 ± 0.30 | 0.97 ± 0.01 | 4.70 | 0.0004 |
*
non-responders assigned latency of 600 sec.