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. Author manuscript; available in PMC: 2013 May 13.
Published in final edited form as: Eur J Neurosci. 2011 May 25;33(12):2228–2237. doi: 10.1111/j.1460-9568.2011.07706.x

Fig. 6.

Fig. 6

Blocking α2-NRs eliminated gasping in the inspiratory island preparation in vitro. (A) Schematic of the inspiratory island that generated rhythmic inspiratory activity. (B) Gasping was evoked after application of hypoxic aCSF. (C1) Characteristics of gasping in the inspiratory island. VRG burst during application of hypoxic aCSF in black and in control in grey. (C2 and 3) Histograms show fictive eupnea (open bars) and fictive gasps (solid bars). C2 shows the shorter rise time of fictive gasps and (C3) the shorter burst duration. (D) Blockade of alpha-2 noradrenergic receptors prevents generation of gasping in the inspiratory island preparation. *P < 0.05, Mann–Whitney test. Results are expressed as mean ± SEM.