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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Psychopharmacology (Berl). 2012 Apr 13;223(1):1–15. doi: 10.1007/s00213-012-2680-6

Figure 2.

Figure 2

Dose effects of peak increases on participant ratings of four items on the Subjective Effects Questionnaire (upper and middle rows) and peak decreases on two psychomotor measures (lower row). Y-axes: participant rating of Drug Effect, Mentally Slowed Down, Numbness, and Sleepy on a 100-point scale; Circular Lights, number correct; Balance, time in seconds. X-axes: dose in mg/70kg of triazolam and dextromethorphan; PL designates placebo; ‘penul’ and ‘max’ refer, respectively, to the penultimate and maximum doses of dextromethorphan administered to each volunteer; max values are not presented for participant ratings because of missing data. Data points show means; brackets show 1 SEM; filled symbols indicate values that are significantly different from the placebo (p<0.05, planned comparisons).