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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Medchemcomm. 2013 Mar 21;4(5):847–851. doi: 10.1039/C3MD00080J

Figure 2.

Figure 2

HIV-1SF162 infectivity in human astrocytes (HA) was determined based on the relative amount of Tat protein expressed by the virus using a luciferase based assay. Dose response effect was first studied for each compound (See Supporting Information). Values are absorbance ± SEM (x-axis) of three independent experiments at 18 h post-infection [Maraviroc (MVC), 100 nM; naltrexone (NTX), 1.5 μM; bivalent ligand 1, 100 nM; *p < 0.005 vs. uninfected cells (control); $p < 0.05 vs. R5 HIV-1; §p < 0.05 vs. R5 + MVC; p < 0.05 vs. R5 + NTX].