Figure 10.
Locations of peptides involved in SH3 domain unfolding. (A) Peptides 98–105 (blue) and 115–132 (red) of Hck SH3 in the context of the near full length down-regulated Hck kinase (PDB 1QCF, [60]). (B) Lyn SH3 (PDB 1W1F, [127]) residues 69–86 (blue), 100–111 (red). (C) α-spectrin SH3 (PDB 1U06, [128]) residues 964–977 (blue) and 995–1014 (red). (D) Hck SH3, derived from panel A (PDB 1QCF, [60]) residues 98–105 (blue) and 115–132 (red) and (E) Lck SH3 (PDB 1LCK, [129]) residues 16–33 (blue) and 44–61 (red). Parts of this figure were derived from Refs. [66] and [72].