Cytokine induction in peripheral blood mononuclear cells stimulated with CpG ODNs loaded onto BNNS and BNNS-CS complexes (50 μg/mL). (A) IL-6 production and (B) TNF-α production.
Notes: The data are presented as the mean ± standard deviation (n = 3). *P < 0.05.
Abbreviations: CS, chitosan; BNNS, boron nitride nanospheres; CS-L, chitosan with a molecular mass of 60–120 kDa; CS-M, chitosan with a molecular mass of 110–150 kDa; CS-H, chitosan with a molecular mass of 140–220 kDa; CpG, cytosine-guanine; ODNs, oligodeoxynucleotides.