Table 2.
Association of FeNO levels with pre-trial illness burden*
| FeNO Quartiles | ||||||
|---|---|---|---|---|---|---|
| Parameter | ≤ 10.5ppb (1st Quartile) N=22 |
10.6ppb to 14.0ppb (2nd Quartile) N=23 |
14.1ppb to 24.4ppb (3rd Quartile) N=21 |
> 24.4ppb (4th Quartile) N=23 |
P-value | |
| Disease burden: | ||||||
| Number of ED visits in past year | 0.8 +/− 1.2 | 1.0 +/− 2.0 | 2.0 +/− 5.2 | 1.1 +/− 1.6 | 0.53 | |
| Number of office visits in past year | 3.1 +/− 1.5 | 4.4 +/− 3.7 | 4.6 +/− 5.1 | 3.6 +/− 3.0 | 0.63 | |
|
Number days of missed school/daycare in past year |
8.9 +/− 21.4 | 4.5 +/− 5.8 | 4.1 +/− 6.6 | 2.9 +/− 4.0 | 0.11 | |
| Medication use in past year: Number (% of children in each quartile) | ||||||
| Inhaled corticosteroid | 10 (58.8%) | 7 (53.8%) | 6 (35.3%) | 8 (57.1%) | 0.62 | |
| Montelukast | 2 (11.8%) | 2 (15.4%) | 1 (5.9%) | 3 (21.4%) | 0.65 | |
|
Any controller (Including oral corticosteroids) |
17 (77.3%) | 13 (56.5%) | 17 (81%) | 14 (60.9%) | 0.56 | |
|
Number of courses of oral corticosteroids in past year: |
0 | 10 (45.5%) | 10 (43.5%) | 6 (28.6%) | 14 (60.9%) | |
| 1 | 5 (22.7%) | 3 (13%) | 5 (23.8%) | 5 (21.7%) | ||
| 2 | 6 (27.3%) | 4 (17.4%) | 6 (28.6%) | 3 (13%) | 0.4 | |
| 3 | 1 (4.5%) | 2 (8.7%) | 4 (19%) | 0 (0%) | ||
| 4+ | 0 (0%) | 4 (17.4%) | 0 (0%) | 1 (4.3%) | ||
| Quality of life Scores: | ||||||
|
PACQLQ overall score (maximum =7) |
6.62 +/− 0.66 | 6.6 +/− 0.6 | 6.5 +/− 0.8 | 6.5 +/− 0.8 | 0.44 | |
|
Peds QL total score (maximum=100) |
0.29 +/− 0.25 | 0.4 +/− 0.4 | 0.4 +/− 0.22 | 0.5 +/− 0.3 | 0.17 | |
*
Data are expressed as means ± standard deviation, except at noted.