Table 3.
Logistic Regression: Demographic and Disease-Related Predictors of Cognitive Impairment in Pediatric Multiple Sclerosis and Clinically Isolated Syndrome (n = 164)a
Demographics + disease- related OR (95% CI) | Significance | |
---|---|---|
Age | 0.92 (0.80–1.06) | 0.25 |
Race nonwhite | 0.87 (0.36–2.10) | 0.87 |
Hispanic ethnicity | 2.05 (0.93–4.56) | 0.08 |
Female | 1.10 (0.52–2.35) | 0.80 |
Parent education | 1.02 (0.99–1.05) | 0.06 |
Disease duration | 1.08 (0.92–1.30) | 0.35 |
Diagnosis RRMS or CIS | 3.60 (1.07–12.36) | 0.04 |
EDSS | 1.47 (1.05–2.06) | 0.03 |
Abbreviations: CI, confidence interval; OR, odds ratio; CIS, clinically isolated syndrome; EDSS, Expanded Disability Status Scale; RRMS, relapsing remitting multiple sclerosis.
The sample (n = 164) were included in the regression based on having complete clinical data (eg, expanded disability status scale, parent education) and 9 of 11 neuropsychological tests complete on the neuropsychological battery.