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. Author manuscript; available in PMC: 2013 May 13.
Published in final edited form as: Nat Genet. 2011 Jun 5;43(7):621–629. doi: 10.1038/ng.848

Figure 3. Functional associations of ncRNAs.

Figure 3

(a) lncRNA expression patterns do not correlate with that of the mRNAs in cis. Histogram of Pearson correlations between each of the 216 ncRNAs and the cis mRNA across 108 samples.

(b) lncRNA expression patterns have positive correlation with neighboring lncRNA transcripts. Histogram of Pearson correlations between each of the 216 ncRNAs and nearby transcripts on the same locus across 108 samples.

(c) Genes co-expressed with lncRNAs are enriched for functional groups in cell cycle and DNA damage response. Module map of lncRNA gene sets (columns) versus Gene Ontology Biological Processes gene sets (rows) across 17 samples (p<0.05, FDR<0.05). A yellow entry indicates that the GO gene set is positively associated with the lncRNA gene set. A blue entry indicates that the GO gene set is negatively associated with the lncRNA gene set. Black entry indicates no significant association. Representative enriched GO gene sets listed.