Table 3.

Risk Factors for Transfusion-associated Circulatory Overload from the Final Multivariable Logistic Regression Model

Variable	Odds Ratio (95% CI)
Chronic renal failure	27.0 (5.2–143)
History of congestive heart failure	6.6 (2.1–21)
Shock before transfusion
Hemorrhagic shock	113 (14.1–903)
Other shock	2.5 (0.8–7.5)
Estimated blood volume* (per liter)	0.51 (0.23–1.1)
Blood products transfused (per unit)	1.11 (1.01–1.22)
Fluid balance per hour (per liter)	9.4 (3.1–28)
Age (per 10 years)	0.78 (0.62–0.99)
Male sex	1.11 (0.35–3.5)
Hospital (Mayo Clinic vs UCSF)	11.2 (1.98–63)

CI = confidence interval; UCSF = University of California, San Francisco Medical Center.

^*Nadler formula.