Table 1.
ACL (n = 169) | Controls (n = 260) | ACL (n = 169) | Controls (n = 260) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Allele |
n |
F % |
n |
F % |
P-value |
Pc-value |
OR |
95%CI |
Allele |
n |
F% |
n |
F% |
P-value |
Pc-value |
OR |
95%CI |
HLA – A* |
|
|
|
|
|
|
|
|
HLA-B* |
|
|
|
|
|
|
|
|
01 |
37 |
10.9 |
47 |
9.0 |
ns |
- |
|
|
07 |
20 |
5.9 |
38 |
7.3 |
ns |
- |
|
|
02 |
95 |
28.1 |
127 |
24.4 |
ns |
- |
|
|
08 |
16 |
4.7 |
34 |
6.5 |
ns |
- |
|
|
03 |
30 |
8.8 |
56 |
10.8 |
ns |
- |
|
|
13 |
1 |
0.3 |
9 |
1.7 |
ns |
- |
|
|
11 |
23 |
6.8 |
26 |
5.0 |
ns |
- |
|
|
14 |
15 |
4.4 |
22 |
4.2 |
ns |
- |
|
|
23 |
18 |
5.3 |
22 |
4.2 |
ns |
- |
|
|
15 |
26 |
7.7 |
48 |
9.2 |
ns |
- |
|
|
24 |
37 |
10.9 |
62 |
11.9 |
ns |
- |
|
|
18 |
17 |
5.0 |
36 |
6.9 |
ns |
- |
|
|
25 |
4 |
1.2 |
13 |
2.5 |
ns |
- |
|
|
27 |
7 |
2.1 |
8 |
1.5 |
ns |
- |
|
|
26 |
11 |
3.2 |
18 |
3.5 |
ns |
- |
|
|
35 |
58 |
17.2 |
68 |
13.1 |
ns |
- |
|
|
29 |
9 |
2.6 |
28 |
5.4 |
ns |
- |
|
|
37 |
1 |
0.3 |
5 |
1.0 |
ns |
- |
|
|
30 |
11 |
3.2 |
25 |
4.8 |
ns |
- |
|
|
38 |
10 |
3.0 |
15 |
2.9 |
ns |
- |
|
|
31 |
18 |
5.3 |
19 |
3.7 |
ns |
- |
|
|
39 |
13 |
3.9 |
18 |
3.5 |
ns |
- |
|
|
32 |
8 |
2.3 |
16 |
3.1 |
ns |
- |
|
|
40 |
18 |
5.3 |
16 |
3.1 |
ns |
- |
|
|
33 |
5 |
1.5 |
15 |
2.9 |
ns |
- |
|
|
41 |
2 |
0.6 |
6 |
1.2 |
ns |
- |
|
|
34 |
3 |
0.9 |
5 |
1.0 |
ns |
- |
|
|
42 |
2 |
0.6 |
6 |
1.2 |
ns |
- |
|
|
36 |
2 |
0.6 |
2 |
0.4 |
ns |
- |
|
|
44 |
43 |
12.7 |
46 |
8.9 |
ns |
- |
|
|
39 |
1 |
0.3 |
- |
- |
ns |
- |
|
|
45 |
0 |
- |
12 |
2.3 |
0.0046 |
0.1426 |
- |
- |
66 |
3 |
0.9 |
1 |
0.2 |
ns |
- |
|
|
46 |
0 |
- |
4 |
0.8 |
ns |
- |
|
|
68 |
19 |
5.62 |
35 |
6.7 |
ns |
- |
|
|
47 |
0 |
- |
1 |
0.2 |
ns |
- |
|
|
74 |
4 |
1.9 |
3 |
0.6 |
ns |
- |
|
|
48 |
3 |
0.9 |
2 |
0.4 |
ns |
- |
|
|
HLA-DRB1* |
|
|
|
|
|
|
|
|
49 |
8 |
2.4 |
8 |
1.5 |
ns |
- |
|
|
01 |
23 |
6.8 |
42 |
8.1 |
ns |
- |
|
|
50 |
8 |
2.4 |
14 |
2.7 |
ns |
- |
|
|
03 |
32 |
9.5 |
61 |
11.7 |
ns |
- |
|
|
51 |
29 |
8.6 |
44 |
8.5 |
ns |
- |
|
|
04 |
40 |
11.8 |
56 |
10.8 |
ns |
- |
|
|
52 |
10 |
3.0 |
11 |
2.1 |
ns |
- |
|
|
07 |
39 |
11.5 |
67 |
12.9 |
ns |
- |
|
|
53 |
7 |
2.1 |
8 |
1.5 |
ns |
- |
|
|
08 |
26 |
7.7 |
30 |
5.8 |
ns |
- |
|
|
54 |
1 |
0.3 |
3 |
0.6 |
ns |
- |
|
|
09 |
4 |
1.2 |
4 |
0.8 |
ns |
- |
|
|
55 |
8 |
2.4 |
12 |
2.3 |
ns |
- |
|
|
10 |
5 |
1.5 |
10 |
1.9 |
ns |
- |
|
|
56 |
2 |
0.6 |
1 |
0.2 |
ns |
- |
|
|
11 |
45 |
13.3 |
81 |
15.6 |
ns |
- |
|
|
57 |
7 |
2.1 |
12 |
2.3 |
ns |
- |
|
|
12 |
3 |
0.9 |
10 |
1.9 |
ns |
- |
|
|
58 |
6 |
1.8 |
10 |
1.9 |
ns |
- |
|
|
13 |
51 |
15.1 |
54 |
10.4 |
0.0431 |
0.6465 |
1.53 |
1.01-2.31 |
73 |
0 |
- |
1 |
0.2 |
ns |
- |
|
|
14 |
19 |
5.6 |
40 |
7.7 |
ns |
- |
|
|
81 |
0 |
- |
2 |
3.9 |
ns |
- |
|
|
15 |
34 |
10.1 |
44 |
8.8 |
ns |
- |
|
|
|
|
|
|
|
|
|
|
|
16 | 17 | 5.0 | 21 | 4.0 | ns | - |
n = number of times the allele occurs; F = allele frequency; P-value = calculated by Fisher’s exact test; Pc-value = value of p corrected by Bonferroni correction; OR = odds ratio; 95%CI = 95% confidence interval; ns= not significant (p > 0.05).