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. 2013 Apr 18;13:180. doi: 10.1186/1471-2334-13-180

Table 3.

Acquisition and clearance of Streptococcus pneumoniae carriage in 3 day-care centres in Finland, 2001–2002

 
 Clearance
 Acquisition in non-carrying children
 Acquisition in carrying children
Target serotype Exposure1 Events Person-time2 Events Person-time3 Events Person-time4
9V
 Yes
 7
 12
 7
 56
 1
 14
No
 3
 3
 6
 300
 1
 83
18C
 Yes
 7
 16
 9
 87
 0
 11
No
 4
 4
 1
 269
 0
 81
3
 Yes
 1
 3
 6
 105
 1
 30
No
 8
 11
 4
 251
 0
 68
15BC
 Yes
 1
 4
 1
 77
 0
 19
No
 5
 12
 7
 279
 0
 77
19A
 Yes
 4
 5
 0
 35
 0
 8
No
 3
 3
 2
 321
 0
 96
19F
 Yes
 2
 3
 1
 28
 1
 8
No
 2
 8
 2
 328
 1
 93
11A
 Yes
 2
 2
 0
 18
 0
 8
No
 0
 4
 1
 338
 5
 98
14
 Yes
 0
 0
 0
 12
 0
 5
No
 3
 4
 2
 344
 1
 103
35F
 Yes
 0
 1
 1
 40
 0
 13
No
 1
 3
 1
 316
 2
 95
38
 Yes
 0
 0
 0
 24
 0
 13
No
 2
 3
 2
 332
 0
 96
22
 Yes
 0
 0
 0
 20
 0
 0
No
 1
 5
 0
 336
 2
 107
33
 Yes
 0
 0
 0
 0
 0
 0
No
 0
 0
 2
 356
 0
 112
6A
 Yes
 0
 0
 0
 8
 0
 6
No
 1
 1
 1
 348
 0
 105
6B
 Yes
 0
 0
 0
 12
 0
 7
No
 1
 2
 1
 344
 0
 103
7
 Yes
 0
 0
 0
 9
 0
 1
No
 1
 1
 1
 347
 0
 110
10
 Yes
 0
 0
 0
 4
 0
 2
No
 1
 1
 0
 352
 0
 109
18B
 Yes
 0
 0
 0
 3
 0
 1
No
 1
 1
 0
 353
 0
 110
35B
 Yes
 0
 0
 0
 0
 0
 0
No
 0
 0
 1
 356
 0
 112
9N
 Yes
 0
 0
 0
 0
 0
 0
No
 0
 0
 1
 356
 0
 112
165
 Yes
 0
 0
 0
 7
 0
 4
No
 0
 0
 0
 349
 0
 108
Total: Yes
 24
 46
 25
 545
 3
 150
No 37
 66
 35
 6575
 12
 1978
61 112 60 7120 15 2128

The crude estimates of the model parameters are (cf. Appendix): the transmission rate β^=25−κ^×545/85.26=0.26 (per month); the community acquisition rate per serotype (in non-carrying children) κ^=35/6575=0.005 (per month); the clearance rate of carriage μ^=61/112=0.54 (per month); the competition parameter φ^=12/1978/35/6575=1.14. For parameter β, the denominator (85.26) is not directly readable from the data as presented in the table. Only samples from two consecutive visits were considered (85% of the scheduled pairs of consecutive visits).

1 Exposure is here defined as the presence of at least one carrier of the target serotype in the other attendees in the room.

2 Person-time here is the total time, in months, spent carrying pneumococcus overall (total row) or a specific serotype (serotype rows) stratified by the presence or absence of other carriers of the specific serotype.

3 Person-time here is the total time, in months, spent as a non-carrier, stratified by exposure to the specific serotype. For the total row, the time is a sum of serotype-specific person-times.

4 As in 2 but for children carrying pneumococcus.

5 Sampled only once in a child which was missing at the next visit.