Table 1.
Percentage of genes with signal peptides or transmembrane domains
| n | Absence of signal peptides | P | Absence of transmembrane domains | P | |
|---|---|---|---|---|---|
| Rats | |||||
| IL genes | 65 | 92.3% | 0.003 | 93.8% | 6 × 10-4 |
| NIL genes | 8,410 | 75.7% | 74.6% | ||
| Parental genes | 637 | 93.4% | < 10-16 | 90.1% | < 10-16 |
| Other genes | 7,838 | 74.4% | 73.6% | ||
| Mice | |||||
| IL genes | 42 | 95.2% | 0.004 | 92.9% | 0.015 |
| NIL genes | 8,410 | 74.6% | 75.5% | ||
| Parental genes | 1,013 | 91.3% | < 10-16 | 88.3% | < 10-16 |
| Other genes | 7,439 | 72.5% | 73.9% |
Absence of a signal peptide or a transmembrane domain indicates mRNA translation on free cytoplasmic ribosomes. Pearson's chi-square test was used to calculate the P values. IL: intron-lost; NIL: no-intron-lost genes; Parental genes: parental genes of processed pseudogenes.