Figure 8. Effects of chronic intermittent ethanol or saline exposure during adolescence or adulthood on response rate (top panel, A) and average pellets per session (bottom panel, B) after an acute ethanol challenge.

Data are expressed as group mean + SEM (n = 6 adolescent-saline, n = 6 adolescent-CIE, n = 5 adult-saline, n = 5 adult-CIE). Asterisks denote a significant difference between rats exposed to CIE or saline as adults versus adolescents during acute ethanol challenge at specific doses (simple effects ANOVA, p<0.05).