Figure 1. Fracture femoral (A) stiffness and (B) maximum strength.

Pten mutants had significantly higher stiffness at 28 d PF and maximum strength at 14, 21, and 28 d PF in fractured femurs. The stiffness and strength increased for both the wild-type and mutant groups during the healing process. (*p<0.05, **p<0.01, and ***p<0.001 WT to Mut at the time point.).