Table 1.
Summary of experimental restraints and structural statistics for murine SOCS3 SOCS box in complex with elonginBC
| No. of distance restraints | 1542 | |
| Intraresidue (i=j) | 436 | |
| Sequential (|i−j|=1) | 445 | |
| Medium range (1<|i−j|<4) | 242 | |
| Long range (|i−j|>4) | 307 | |
| Intermolecular | 112 | |
| Total dihedral angle restraints | 227 | |
| ϕ angles | 113 | |
| ψ angles | 114 | |
| Violations | ||
| NOE violations >0.4 Å | 2 | |
| Dihedral violations >5° | 2 | |
| Deviations from ideal geometrya | ||
| Bonds (Å) | 0.002549±0.00003 | |
| Angles (deg) | 0.583±0.003 | |
| Impropers (deg) | 0.409±0.003 | |
| Average RMSD to mean atomic coordinates (Å) | Ordered regionsb | Total |
| Backbone (N, Cα, C′) | 1.13 | |
| All heavy atoms | 1.68 | |
| Ramachandran plotc | ||
| Most favored (%) | 80 | 73.9 |
| Additionally allowed (%) | 13.5 | 17.7 |
| Generously allowed (%) | 4.7 | 6.1 |
| Disallowed (%) | 1.7 | 2.2 |
a
The values for the bonds, angles, and impropers show the deviations from ideal values based on perfect stereochemistry.
b
Ordered regions were considered as 1–15 (SOCS box), 1–82 (eloB), 17–44 and 59–112 (eloC).
c
As determined by the program PROCHECK-NMR for all residues except Gly and Pro.